Any parents out there that their kids hate them?

Well in my sisters case, she has always blamed herself that her only daughter grew up to be a hateful vendictive person, but I have tried to tell her that it was nothing she did. The girl has a emotional problems to do and say the things she does to her and her husband! After supporting her to the point of losing everything,their whole way of life, she still treats them terribly. The only way her daughter could ever turn herself around and repair so much damage would be to first admit that she has a problem, then get some help, but that will never happen. Just wish that her mom would stop blaming herself for something that she had nothing to do with.