New Severe Warnings About Arthritis Type Medications

@pyewacket (43962)
United States
September 11, 2008 4:54pm CST
This is precisely why I don't rush out to get prescribed medications. You listen to the ads on TV about this medication and that medication and listen to the possible side effects and it's like why the hell would you want to take this? It's seems more and more "miracle" drugs sooner or later will have an announcement of placing severe warnings to the potential of sometimes life-threatening side effects when a certain medication is taken. The latest group are several medications usually prescribed for arthritic conditions such as rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, plaque psoriasis, ankylosing spondylitis, and Crohn's disease. The medications involved are [b]Humira, Cimzia, Enbrel, and Remicade [/b] From what I've read, severe warnings have been around for Humira in particular as early as 2004, and it was usually a combination of taking Humira with other types of medications, in other words, drug interactions. As usual our dear sweet FDA is only getting around to alert the medical community of the risks involved in taking such medications, like Humira. The former warnings in 2004 were as follows: (Quote) [i]..."rare cases of hypersensitivity reactions, blood cell deficiencies, and problems from taking Humira with another rheumatoid arthritis drug, Kineret. Other problems include "rare" cases of anaphylaxis, which is a sudden, life-threatening allergic reaction. The new warning says Humira should be "discontinued immediately" if anaphylactic or other serious reactions occur, noting that overall, about 1% of patients taking Humira in clinical trials had allergic reactions..." [/i] You can see the full article here http://www.webmd.com/rheumatoid-arthritis/news/20041109/new-warnings-on-humira-drug-label The new warnings just issued out September 4, 2008 includes a potential for life-threatening fungal infections...to quote another article (Quote) [i]The Food and Drug Administration (FDA) has ordered the manufacturers of Humira, Cimzia, Enbrel, and Remicade to strengthen the warnings about the products because the medications are associated with a risk for opportunistic fungal infections, specifically histoplasmosis. Some patients have died from these infections. [/i] The full article is here. http://www.lawyersandsettlements.com/case/makers-of-tnf-blockers-to-strengthen-warnings-about.html?ref=newsletter_bca_makers-of-tnf-blockers-to-strengthen-warnings-about And from the FDA Website itself here are a few more quotes: [i]The U.S. Food and Drug Administration today announced that the manufacturers of Humira, Cimzia, Enbrel, and Remicade must strengthen the existing warnings, in the Warnings and Precaution sections of the drugs' prescribing information and Medication Guides, on the risk of developing opportunistic fungal infections. Some patients with invasive fungal infections have died. The four drugs, known as tumor necrosis factor alpha blockers (TNF-alpha blockers), which suppress the immune system, are approved to treat a variety of conditions which may include rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, plaque psoriasis, ankylosing spondylitis, and Crohn's disease. The FDA reviewed one reported case of histoplasmosis in a patient taking Cimzia. The FDA also has received reports of cases of coccidioidomycosis and blastomycosis, including deaths, in patients treated with TNF blockers. [/i] The full article is here http://www.fda.gov/bbs/topics/NEWS/2008/NEW01879.html {Warning...these links are related to articles and are NOT referral links} I bring this all up since I know many mylotters may have arthritic type conditions and may even be taking some of these medications. So to make this a discussion...One, do any of you take these medications. If not, in general, have you ever been prescribed a medication in which you had a severe reaction to, or gave more complications to the health problem it was supposed to solve?
5 people like this
7 responses
@ElicBxn (60016)
• United States
11 Sep 08
Honestly, the only time I stopped taking a medicine was because it WASN'T working. In fact, years later my dad was given the same medicine and it didn't work for him either. I told him that was one that was given me after the car accident and I stopped taking it and demanded a new medicine because that one did nothing. My dad then talked to his doctor and the medication was changed. In many ways my dad and I had simular problems with medication - Tylenol did NOTHING for us and whatever this med was didn't either. Since its been over 20 years since then I can't remember the medicine now. When I was in the hospital they wanted to give me Tylenol for the pain in my head - I told them that I wouldn't take it because it didn't help me, they gave me moriphine for the pain in my head and that helped - alot.
3 people like this
@pyewacket (43962)
• United States
11 Sep 08
I've never taken Tylenol or Advil, or Aleve since I've heard even they can have "complications"--just take good ole aspirin for most of my problems. I was once given an antibiotic and it too didn't do anything for me...I had to wind up going back to my doctor to get a different prescription (it was for a bout of bronchitis)
3 people like this
@ElicBxn (60016)
• United States
12 Sep 08
I take Aleve - a lot of them. I took alot of asprin - enough to have my ears still ringing some days. I take less Aleve than I ever did asprin for more relief. Since I'm not going to die from them, I'm not going to worry about it.
3 people like this
@ElicBxn (60016)
• United States
12 Sep 08
I don't have artritius, I have fibromyalgia. We are talking pain that I can not take the pain meds normally prescibed. I'm not going to live long enough to worry about other stuff if I don't get relief now from my pain.
1 person likes this
12 Sep 08
Hi pye, How awful all those medications with so much side affects, its a good thing I only take asthma inhalers and nothing else, thy should do more teat on those medicine befor putting them out on sales. Tamara
3 people like this
@BarBaraPrz (16804)
• St. Catharines, Ontario
12 Sep 08
I had been taking naproxen but had to discontinue it because of excessive bruising. (How excessive? I looked at my hand and a bruise appeared while I watched. I guess my eyetracks were too heavy.) Then I took celebrex but had to discontinue that because I developed hypersensitivity to the sun while on it. I'm talking itchy red welts on exposed skin... I'm back to glucosamine and tylenol.
2 people like this
@Opal26 (17694)
• United States
12 Sep 08
Wow pye! That's really scary! I am thankfully not taking any of these medications. I have osteoarthritis. It's extremely painful, but I was given Ibuprofen and Tylenol#3 with Codeine. I was originally given Celebrex which they found problems with and I believe no longer prescribing??? I don't know. That was quite awhile back. I don't trust those meds so I prefer not to take anything unless I absolutely have to. After I sprained my already injured right knee I was put on Ibuprofen 600 mg for pain. It worked a little, but I really didn't want to take anything stronger. I was having increased pain and the doctor gave me Tylenol #3 with Codeine but, advised that I would need to be seen by a Pain Management Physician if I was going to take that for an extended period of time. I assured him that I wasn't going to. I am very afraid of these meds because everytime you start to take them you find out a few years later that something has been found wrong with them.
@pyewacket (43962)
• United States
12 Sep 08
My doctor wanted to give me Celebrex....before I got it filled I looked it up on the computer and when it said the potential side effects are blood clots, strokes and heart attacks said nope thanks I was once taking very, very low doses of theophylline which is an asthma medication..I don't have asthma but lousy sinuses ..LOL...my doctor thought it would help me better than the usual sinus medications. Well like I said I took it in very, very small doses and good thing...but even so my blood pressure readings would be rather high making it look like I had high blood pressure (I didn't)...once I stopped taking it my blood pressure became normal..then a few years ago they pulled it off the market...why? It could sometimes trigger cardiac arrest...oh, gee, great
• Canada
12 Sep 08
This is actually scary to read just because I do have a lot of health problems and have to take a lot of medication ( so they tell me ) or they say it will make things much worse for me and that there is a good possiblity without the medication that I would die !! I have arthritis but refuse to take anything for that because years ago they tried me on all these medications that I found did nothing for the pain and I couldn't see taking a prescription for nothing as it was not working to begin with and arthritis is not life threatening . I am not sure if any of these were one's I had taken years ago but I am now glad I made the decision to suffer rather then take something that didn't seem to help and if it did very little . We are told so often to take this or take that and we believe that it is safe because it is prescribed by a doctor and if you can't trust your doctor to treat you right then who do we trust ?
1 person likes this
@howard96h (11665)
• New York, New York
12 Sep 08
My mother has a friend who is 96 years old and when my mother asks her what is her secret living a healthy life she says "I REFUSE to take any prescription medications"! She believes this is what has kept her healthy all of her life.
1 person likes this
@pyewacket (43962)
• United States
12 Sep 08
That woman sounds like my great-grandmother..LOL. Have to thank you..your email gave me the inspiration for this discussion
@rowe0525 (677)
• China
12 Sep 08
sorry i am i do not know much about that iam a newcomer