finite element method-stress analysis of tubesheet of shell-&-tube heat exchange

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I have undertaken a project. Its objectives are- 1) Stress(mechanical and thermal loads) analysis of tubesheets of shell-and-tube heat exchangers using manual finite element methods 2) Verification of the above stress analysis using ANSYS software. I would like to know about all the stresses that are to be taken into account while formulating the equations using finite element methods and other relevant information regarding my topic.