Pain killers, how horrible!!!!  

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention

A rare symptom can be Yellow eyes or skin

Overdose can cause Diarrhea; increased sweating; loss of appetite; nausea or vomiting; stomach cramps or pain; swelling, pain, or tenderness in the upper abdomen or stomach area

People should always ask their Doctor about any medications that are prescribed and if buying "over the counter" should talk to the pharmacist/chemist to make sure they know the potential side effects as well as any possible interaction with other medications they are taking.

I seldom take any medication for headaches, but then I do take a few prescription medications for other conditions. I make sure that everything I take does not have an adverse effect on anything else that I am taking. A lot of people take medicines, without asking the relevant questions. If the patient is not comfortable talking to their doctor about adverse reactions from medications, it is time to find a doctor they can talk to.

Thanks for sharing this information with us, and it might be of help to people who are not as lucky as I am with my Doctor and Pharmacist/Chemist. :)

may be....!!

I always rough it out when i'm in minor pain, i don't like painkillers and i would never consider taking them since they are not a solution to the problem that causes the pain. Maybe i have a high pain threshold or something but i usually deal with the pain by simply ignoring it.

shocking news

Pain killers are absolutely disgusting... Jus for name sake they are called painkillers... I've heard consumption of excess painkillers leads to liver cancer...since then i've stopped takin pain killers... i am accustomed to hell lotta pain in my back... but i manage these days

Viagra cancels painkiller side effects, but might have side effects of its own

28 October 2005


The impotence drug Viagra could be used to block gastric inflammation caused by drugs such as aspirin and ibuprofen, report researchers.

Nonsteroidal anti-inflammatory drugs (NSAIDs), including aspirin, ibuprofen, and indomethacin, are effective against inflammation, but their clinical use is limited by potential gastric side effects, including stomach ulcers. Now, pre-clinical data from Brazil suggests that patients who would otherwise benefit from regular doses of NSAIDs could avoid the risk of gastric damage.

NSAIDs prevent pain and inflammation by inhibiting the pro-inflammatory cyclooxygenase enzymes COX-1 and COX-2, which produce prostaglandins in the body. Prostaglandins are involved in a number of inflammatory processes. COX-1 disruption is thought to have a negative effect on the prostaglandin-regulated mucous lining of the gastrointestinal tract, while COX-2 inhibition provides pain relief.

Camila Santos and Marcellus Souza at the Federal University of Ceará, Brazil investigated whether Viagra (sildenafil) could protect the gastrointestinal tract in rats dosed with the NSAID indomethacin. The indomethacin reduced gastric blood flow and increased the adhesion of inflammatory white blood cells, two possible precursors to gastric side effects. Sildenafil corrected both of these effects, possibly through its nitric oxide-generating properties.

Since both sildenafil and NSAIDs are already licensed, human trials would progress rapidly, says Adriano Rossi from the MRC Centre for Inflammation Research at the University of Edinburgh.

Rossi welcomes the findings, but notes that this treatment to reduce one set of side effects might come with side effects of its own. ‘Ideally the dose would be regulated such that it only had significant effects on the stomach,’ Rossi told Chemistry World. ‘However, side effects like unwanted erections are a possibility.’

Attempts to inhibit COX-2 alone with drugs such as the withdrawn NSAID Vioxx have not provided the solution (Chemistry World, March 2005, p10). Meanwhile Viagra is currently in clinical trials for hypertension, and shows pre-clinical promise in heart attack, stroke, diabetes and congestive heart failure. Helen Carmichael

pain killers are not horrible. how could they be? they actually help you to relax at the right doses. you need to find the right dose for you, in order, to avoid certain side effects like frying your liver.

Thanks for the info! I pretty much knew all this. What about perscription pain killers?

Well, NSAID's aren't really "painkillers" like the traditional term. They are just anti-inflammatories, not opiates or addictive pills that actually numb you to pain. Theese just alleviate pain. They aren't addictive like real painkillers, don't make you groggy or doped up. They're also over teh counter, not prescription. These are drugs like ibuprofen, Advil, Excedrin, etc.

The only danger is from overdose or dosing with alcohol. If you use them like you're supposed to, then you're fine.