Laron Syndrome Benefits

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Laron Syndrome is a rare form of Dwarfism,that mostly affects villagers living in remote areas, one such group of around 99,in Ecuador, were studied for about one quarter of a century, by an Ecuadorean physician and diabetes specialist. Most such villages are inhabited by Indians, but these were Europeans, with Spanish surnames,probably the descendants of conversos, Sephardic Jews from Spain and Portugal. As Dr. Guevara-Aguirre acquired health data on these people, a remarkable pattern:evolved, though cancer was frequent among people who did not have the Laron mutation, those who did almost never got cancer,nor diabetes, although many were obese,and exhibited other markers which often preclude the condition. He then teamed up with a researcher on aging at the University of Southern California,who found their youth and longevity, remarkable, and an opportunity to explore in people the genetic mutations that researchers had already found could make laboratory animals live much longer than usual. Dr. Longo said he believed that having very low levels of IGF-1 was the critical feature of the Laron patients’ freedom from age-related diseases. A strain of mice bred by John Kopchick of Ohio University has a defect in the growth hormone receptor gene, just as do the Laron patients, and live 40 percent longer than other lab mice. " Could be the next celebrity, 'must-have" source:wtf.com