depression,money,business,advise

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I have a friend. He is hard working and intelligent. But he is an unfortunate fellow. He tried so many businesses and jobs but the result is debt. He cannot lead a life according to his actual potential. He can't earn money in any way. Now he is totally depressed and told be he is bored with this life full of failures and disappointment and wish to end up every thing. Yes, he wish to give a full stop to his life. By hearing this I was really shocked. I wish to give him a good advise about value of life.But I don't know how to give an advise to such a disappointed person.Can anybody help me?