do help me organise a news letter..??

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hi there to everyone...we are starting a news letter on health and related topics esp, diabetes and cholesterol... pls help us organise the news letter..!! what all do we need to do before starting it..?? do we have to register it..?? how to introduce it..?? who all to introduce it to, patients or doctors and general public..?? what more do we need to know before publishing it..?? we are planning to print it from our own printer, is it ok..???