pituitary

Hypopituitarism: This the Common Pituitary Disorder :) Pituitary adenomas are the most common cause of hypopituitarism, but other causes include parasellar diseases, pituitary surgery, radiation therapy, and head injury. The classic sequential loss of pituitary hormones secondary to a mass effect is in the following order: growth hormone (GH), gonadotropins (LH, FSH), adrenocorticotropic hormone (ACTH) and thyroid-stimulating hormone (TSH).1 The underlying etiology for typical earlier loss of GH and gonadotropins is not known. Isolated deficiencies of various anterior pituitary hormones can also occur. Diabetes insipidus is almost never seen in patients with microadenoma, but it rarely occurs in those with larger tumors extending superiorly, affecting the synthesis of ADH.