Is ignorance really bliss?

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There is an age old saying that ignorance is bliss. Have you ever a situation which substantiates this saying? One which I remember was when the doctor in his sixties, whom I had visited to treat me, for which seems a common throat infection, received his own Renal Profile report and realised his kidneys have failed - he was so much heartbroken that he refused to see any patients. He knew his days were numbered.