The Universe ~ Top Ten Questions

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I am interested in reading MyLotters Top Ten Questions About the Universe. With the Universe being the icon of all that is "vast," and MyLot being a symbol of vast questions and opinions, the two should partner up pretty well. I hope MyLotters will respond in a list form (from 1 - 10), with their questions about the Universe. I expect that some amazingly interesting discussions will come about, simply based on the thought that the questions themselves will evoke. Example Question: In terms of an infinite universe, what fraction of infinite time, has science calculated (if any) as a means to estimate what fraction of knowledge modern man now has toward understanding the expanse of the universe. Philosophical Question? Maybe.