what do u know about MG?

China
March 12, 2009 2:45am CST
Myasthenia gravis (literally "serious muscle-weakness"; from Greek µ?? "muscle", "weakness", and Latin gravis "serious"; abbreviated MG) is a neuromuscular disease leading to fluctuating muscle weakness and fatiguability. It is an autoimmune disorder, in which weakness is caused by circulating antibodies that block acetylcholine receptors at the post-synaptic neuromuscular junction,[1] inhibiting the stimulative effect of the neurotransmitter acetylcholine. Myasthenia is treated medically with cholinesterase inhibitors or immunosuppressants, and, in selected cases, thymectomy. At 200–400 cases per million it is one of the less common autoimmune disorders
4 people like this
5 responses
• China
12 Mar 09
The most widely accepted classification of myasthenia gravis is the Myasthenia Gravis Foundation of America Clinical Classification:[2] Class I: Any eye muscle weakness, possible ptosis, no other evidence of muscle weakness elsewhere Class II: Eye muscle weakness of any severity, mild weakness of other muscles Class IIa: Predominantly limb or axial muscles Class IIb: Predominantly bulbar and/or respiratory muscles Class III: Eye muscle weakness of any severity Moderate weakness of other muscles Class IIIa: Predominantly limb or axial muscles Class IIIb: Predominantly bulbar and/or respiratory muscles Class IV: Eye muscle weakness of any severity, severe weakness of other muscles Class IVa: Predominantly limb or axial muscles Class IVb: Predominantly bulbar and/or respiratory muscles (Can also include feeding tube without intubation) Class V: Intubation needed to maintain airway
4 people like this
• China
12 Mar 09
The hallmark of myasthenia gravis is fatiguability. Muscles become progressively weaker during periods of activity and improve after periods of rest. Muscles that control eye and eyelid movement, facial expression, chewing, talking, and swallowing are especially susceptible. The muscles that control breathing and neck and limb movements can also be affected. Often the physical examination is within normal limits
3 people like this
@Ted3_uk (114)
12 Mar 09
You know what.. I think that at least 50% of all prolonged illness that is not easy to find the cause to is caused by the mycoplasma virus?! Why is there not more work done into this type of virus| I belive it uses its tiny tiny little arm to reach inside our cells and pick out indivdual ammino acids that make up our DNA codes... it then 'eats' the bit of code and places it in its on DNA stand... Then takes the bit that its just removed from its own DNA and places it back inside our cell completeing the code, but with 1 random bit in it.... To people they seem to only have a cold or flu, but end up with prolonged problems for a long time after, such as ME, or lung and heart function problems diabetes||| I think this is correct? But is this a lie?? You could have the mycoplasma virus and then up as a worse diffrent virus such as hepititus or aids???
• China
12 Mar 09
The onset of the disorder can be sudden. Often symptoms are intermittent. The diagnosis of myasthenia gravis may be delayed if the symptoms are subtle or variable. In most cases, the first noticeable symptom is weakness of the eye muscles. In others, difficulty in swallowing and slurred speech may be the first signs. The degree of muscle weakness involved in MG varies greatly among patients, ranging from a localized form, limited to eye muscles (ocular myasthenia)
2 people like this
@rapatod (20)
• China
12 Mar 09
to a severe or generalized form in which many muscles - sometimes including those that control breathing - are affected. Symptoms, which vary in type and severity, may include asymmetrical ptosis (a drooping of one or both eyelids), diplopia (double vision) due to weakness of the muscles that control eye movements, unstable or waddling gait, weakness in arms, hands, fingers, legs, and neck, a change in facial expression, dysphagia (difficulty in swallowing), shortness of breath and dysarthria (impaired speech, often nasal due to weakness of the velar muscles).
1 person likes this