Antimatter

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Was reading Angels and Demons .. It says that this trap which has antimatter suspended on it using magnets, will soon run out of power, and will anhillate. Its an amount big enough to anhillate Vatican City (lol) so anyways smart priest takes it up in a copter and lets it anhillate in the sky... What i wanted to know... If a certain amount of matter + anti is anhillated, will it create a vaccum and cause everthing to be "scuked" in its direction?