How do you clean your eyeglasses?

I have wire rim glasses and I have found the disgusting green goo that collects in the crevices to be rather sickening. How do you clean this? Do you soak your glasses in a solution? Clean them with a wipe? I have been known to take alcohol and qtips to them. However, I believe if I could find a solution to soak them in, it would be much more effective.