Caterpillar used to grow flu vaccine!
By jennybianca
@jennybianca (12912)
Australia
April 11, 2007 2:20am CST
I thought this was very interesting:A FLU vaccine grown in caterpillar cells instead of the usual risky and uncertain method based on chicken eggs was not only safe but effective in people, US researchers reported today.
They said their findings suggest a possible short-cut to making flu vaccines, focusing on a single protein in the flu virus.
Dr John Treanor, of the University of Rochester in New York, who led the study, believes the vaccine may be quicker and easier to make than current vaccines and might help create a bigger supply of vaccines to fight the common seasonal flu as well as a future pandemic.
“We currently don't have enough vaccine in the US to vaccinate everybody that we would like to vaccinate,” Dr Treanor said.
“Anything that we can can do to increase the vaccine supply is useful.”
His team tested a vaccine called FluBl0k that is made by privately held Protein Sciences Corp of Meriden, Connecticut.
It is grown in a batch of cells taken from the fall armyworm, a kind of caterpillar.
“The company has actually taken those cells and further fooled around with them to make them better for making vaccines,” Dr Treanor said.
Writing in the Journal of the American Medical Association, Dr Treanor and colleagues said they tested the vaccine on 460 healthy people aged 18 to 49 during the 2004-2005 flu season.
One-third got a smaller dose of the vaccine, one-third received a larger dose, and one-third received a placebo shot with no vaccine.
Together, the two different doses of vaccine provided 86 per cent protection, comparable to commercially available flu shots, Dr Treanor said.
There were seven cases of flu in the group that got fake vaccines, two cases in the group that received the smaller dose, and no cases in the group that received the higher dose of vaccine.
Experts believe this so-called cell-culture method is the best way to improve the current method of making flu vaccines.
Now, flu vaccines are reformulated every year to match the three most common strains of circulating flu virus.
The virus must be taken from people, purified, and grown in fertilized chicken eggs.
The process takes months and can easily go wrong.
Cell-culture methods can slice one or two months off the production process, Dr Treanor said.
The article is found here:
http://www.news.com.au/adelaidenow/story/0,22606,21537849-912,00.html
1 person likes this
8 responses
@KarenO52 (2950)
• United States
20 May 07
This is good news for those who get the flu vaccine every year. I know a couple of years back, there was a big shortage of the vaccine, and a concern for the elderly and immunosuppresed patients not being able to get the vaccine. They were given first consideration in many places. It took awhile to catch up with everyone who needed it.
1 person likes this
@lordwarwizard (35747)
• Singapore
20 May 07
I don't really follow news on bio breakthroughs. They don't always happen but they do pop up from time to time. Most of the time though, it only matters to use when the benefits filter down to us - half the time, it won't even occur in our lifetime. :P
1 person likes this
@brendalee (6082)
• United States
23 May 07
this is the first I have heard of this and I am only about an hour away from where Dr Treanor is from. I think its amazing at what things they come up with. Who would have thought that a caterpillar was useful in this way.
@pramodthakur (2365)
• India
21 May 07
Till now you have received 7 responses, this will be 8th one. Hope your topic will cross 10 very soon. If vaccine for Flu can be made using Caterpillar, this will be great help to mankind. I think this will be cheaper also as compared to vaccine available. As Caterpillars are available in bulk around us and that too free of cost or say very minimum cost. Though this seems is in testing round but soon will be available at market with less cost. Thanks to Scientist for valuable invention.
@whiteheather39 (24403)
• United States
11 Apr 07
If that proves to be true it would be a great medical discovery as so many people, especially the elderly, die from the 'flu every year due to lack of vaccine.
1 person likes this
@ArienKing (4647)
• India
19 May 07
Actually FLU vaccine grown better in caterpillar cells instead of the usual risky and uncertain method based on chicken eggs was not only safe but effective in people, US researchers said their findings suggest a possible short-cut to making flu vaccines, focusing on a single protein in the flu virus.
@scarlet_woman (23463)
• United States
21 May 07
i didn't know they could do this-it sounds a much safer way with avian flu kicking around.
hopefully they'll be able to make more for people soon.my mom passed up her shot last year so someone older than she could have it instead.










